SynergyRX vs SkinnyRx: Comparing Two Emerging GLP-1 Providers
Two newer providers offering compounded GLP-1 treatment. How do they differ on medications, pricing, and availability?
Lose 1–2 lbs per week
- Personalized medical supervision
- Trusted by over 50,000 patients
- Featured by leading health publications

25% off your first order
- Physician-prescribed GLP-1 medications
- Compounded semaglutide and tirzepatide
- Fast home delivery nationwide
SynergyRX and SkinnyRx are both newer entrants in the GLP-1 telehealth market, offering compounded semaglutide and tirzepatide at competitive prices. While the established players have longer track records, these newer providers often offer unique advantages like broader medication formats and lower introductory pricing. Here's a side-by-side look.
How They Compare
Medication Options
SynergyRX offers both injectable and oral dissolving tablet versions of semaglutide and tirzepatide, plus brand-name options. SkinnyRx focuses on compounded injectable medications.
SYNNERGY RX
- SynergyRX: injectables + oral tablets
- SkinnyRx: compounded injectables
SkinnyRx
- SynergyRX also offers brand-name options
Pricing
Both offer competitive pricing for compounded GLP-1 medications. SynergyRX starts at $199/month for compounded semaglutide and offers a $100 welcome credit. SkinnyRx's pricing is competitive but less publicly detailed.
SYNNERGY RX
- SynergyRX: from $199/month + $100 credit
- SkinnyRx: competitive pricing
SkinnyRx
- Both more affordable than brand-name
Availability
SynergyRX explicitly states availability in all 50 states. SkinnyRx's coverage is broad but state availability should be confirmed during enrollment.
SYNNERGY RX
- SynergyRX: all 50 states confirmed
- SkinnyRx: broad coverage
SkinnyRx
- Check availability during sign-up
Side-by-Side Comparison
| Feature | SYNNERGY RX | SkinnyRx |
|---|---|---|
| Semaglutide | From $199/month | Competitive pricing |
| Tirzepatide | From $349/month | Available |
| Oral Tablets | Yes (ODT available) | Not listed |
| Coverage | All 50 states | Broad coverage |
| Special Offer | $100 welcome credit | Check current offers |
Semaglutide
SYNNERGY RX
SkinnyRx
Tirzepatide
SYNNERGY RX
SkinnyRx
Oral Tablets
SYNNERGY RX
SkinnyRx
Coverage
SYNNERGY RX
SkinnyRx
Special Offer
SYNNERGY RX
SkinnyRx
The Bottom Line
Both SynergyRX and SkinnyRx offer solid entry points to GLP-1 treatment. SynergyRX stands out with its wider range of formats (including oral dissolving tablets) and availability in all 50 states. SkinnyRx offers a streamlined, fast process for patients who know what they want. For either, make sure to verify their compounding pharmacy credentials before enrolling.
Choose SYNNERGY RX if you want
- Injectable and oral tablet options
- Available in all 50 states
- $100 welcome credit
Choose SkinnyRx if you prefer
- Fast, streamlined enrollment
- Simple physician-prescribed process
- Quick home delivery